Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam

FAKTOR - FAKTOR YANG MEMPENGARUHI TINGKAT KELANGSUNGAN HIDUP 5 TAHUN PASIEN DENGAN KANKER KANDUNG KEMIH DI RSUD DR. ZAINOEL ABIDIN BANDA ACEH

Merysia Karmila — 2025-06-05

ABSTRACT

Background: Bladder cancer is the tenth most common cancer worldwide, and its prevalence is gradually increasing globally. In Indonesia, there are 7,828 new cases of bladder cancer each year, which cause 3,885 deaths. The survival of bladder cancer patients highly depends on many factors. Objective: To identify the factors that influence the 5-year survival rate of patients with bladder cancer at zainoel abidin hospital. Method: An analytical one year study using a retrospective cohort design to analize the factors affecting the 5-year survival rate of bladder cancer patients for 5 years, starting from 2015 until 2019 with medical record data. Result: The average age of the 151 patients was 59±11.9 years, and 126 patients (83,4%) were male. The majority 105 patients (69.54%) were under 65 years old. A total of 127 patients (84.11%) were smokers, 65 patients (43%) with high school degree,

50 patients (33,11%) were self-employed, 96 patients (63.58%) is underweight BMI. Based on stadium of bladder cancer, the majority of patients (34.44%) had T3, and the most common treatment (78.81%) was TURBT and refused to radikal cystectomy. Patient survival rates were influenced by age (P value = 0.00), education level (P value = 0.003), occupation (P value =0,01), treatment (P value = 0,005), and T category (P value = 0.00). Conclusion: Age, education level, occupation, treatment and T category have a significant impact on bladder cancer patients survival rate.

Keywords: Bladder cancer, 5-years survival, Age, Education level, Occupaton, Smokers, BMI, T Category, Treatment.

COMPARISON OF THE EFFECTIVENESS OF MGSO4 30 MG/KGBW AND INTRAVENOUS LIDOCAINE 1.5 MG/KGBW TO PREVENT POST-INTUBATION HEMODYNAMICS FLUCTUATION

MHD Mustafa LBS — 2025-06-05

ABSTRACT

Background: Intubation can cause hemodynamic fluctuations such as increases of systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate. MgSO₄ and lidocaine can be used as premedication drugs to reduce the hemodynamic response to intubation.

Objective: To compare the efficacy of intravenous MgSO₄ 30 mg/kgBW with lidocaine 1.5 mg/kgBW to prevent hemodynamic fluctuations after endotracheal intubation.

Methods: This double-blind randomized controlled trial was conducted in 52 patients meeting the inclusion criteria who underwent surgery with general anesthesia using an endotracheal tube. These subjects were grouped into group A receiving intravenous MgSO₄ 30 mg/kgBW treatment and group B receiving intravenous lidocaine 1.5 mg/kgBW treatment. Hemodynamic fluctuation was recorded 1 minute after intubation.

Results: Subjects receiving MgSO₄had lower increments of SBP (p≤0.001), DBP (p=0.001), MAP (p≤0.001), and HR (p=0.001) than those of receiving lidocaine.

Conclusion: Intravenous MgSO₄ 30 mg/kgBW is more effective than intravenous lidocaine 1.5 mg/kgBW in preventing hemodynamic fluctuations after endotracheal intubation.

RISK FACTORS FOR REGIONAL LYMPH NODE METASTASIS IN PAPILARY THYROID CARCINOMA

Viator Nadeak — 2025-06-05

Abstract

Thyroid cancer is a common malignancy of the endocrine system. One of the current challenges is to control the loco-regional recurrence. Until today, clinical characteristics and histopathological result as predictive factors that can be used to identify patients for prophylactic radical neck dissection are still unclear. Therefore this study aimed to assess the relationship between clinical characteristics and histhopatological result to regional neck lymph node metastases. This was a cross-sectional study, to explain the relationship between clinical characteristic and histopathological result in the incidence of regional neck lymph node metastases. During the study period January 2017 to January 2018, there were 74 patients included in the analysis. The mean age of the patient was 45.31 ± 13,433 years. There were 47 (63.3%) patients with the age categories of <20 and> 40 years old and 27 (36.5%) with age category 20-40 years old. Male patients was accounted for 15 (20.3%) and women 59 (79.7%). The size categories of the tumor were <= 5cm 67 (90.5%) and > 5 cm 7 (9.5%). There were 57 (77.0%) patients with papilary thyroid carcinoma (PTC) and 17 (23.0%) with follicular thyroid carcinoma (FTC). There were 30 (40.5%) positive and 44 (59.5%) negative for Lymphovascular Invasion, For Capsular invasion there were positive 27 (36.5%) and negative 47 (63.5%). There were 45 (60.8%) and 29 (39.2%) patients with positive and negative regional neck lymph node metastases. The factors that influence the occurrence of lymph metastasis were sex, lymphovascular invasion, capsular invasion and histopathology of papillary thyroid carcinoma.

Keywords : Local Recurrence, Lymph Node Metastases, Papilary Thyroid, Risk Factors Carcinoma, Thyroid Carcinoma.

DEVELOPMENT OF VIDEO VIRTUAL REALITY-BASED LEARNING MEDIA FOR PREECLAMPSIA AND ECLAMPSIA CASES IN CLINICAL CLERKSHIP

Sofyan Andri — 2025-06-05

ABSTRACT

Background: preeclampsia and eclampsia are high-risk pregnancy complications that can endanger both the mother and the fetus. The lack of clinical experience among young doctors in managing these conditions can impact their decision-making skills and patient management.

Aims: the aims of this study to give innovative solution to enhance their competence in learning about preeclampsia and eclampsia with Virtual Reality (VR)-based learning media

Methods: The method used in developing this media is the ADDIE model (Analysis, Design, Development, Implementation, Evaluation), which uses a mixed quantitative and qualitative approach. VR media is developed by presenting interactive simulations that allow users to experience various clinical situations realistically and deeply.

Results: Statistical analysis shows that the learning method using VR provides significant advantages in improving theoretical understanding, practical skills, and confidence of clinical clerkship compared to conventional learning methods. These results support the research hypothesis that the use of VR is more effective in the context of learning preeclampsia and eclampsia.

Conclusion: the development of VR-based media has the potential to become an innovative tool supporting medical education, particularly in enhancing the preparedness of young doctors in managing critical obstetric cases

Keywords: Virtual Reality, Learning Media, Pre-eclampsia, Eclampsia, Clinical clerkship

ANALISIS FAKTOR RISIKO PADA KANKER SERVIKS DI RUMAH SAKIT BADAN PENGUSAHAAN BATAM

Acholder T Perdoman — 2025-06-05

ABSTRACT

Background: Cervical cancer is a leading cause of cancer-related death among women worldwide, with a high prevalence, particularly in developing countries. The primary cause of cervical cancer is infection with the human papillomavirus (HPV). Other risk factors include smoking habits, a history of vaginal childbirth, the use of hormonal contraceptives, and age.

Methods: The study uses a quantitative approach with an analytical observational design employing Pearson correlation analysis. Data is collected from patient medical records.

Results: The research results on 183 samples showed a strong correlation (p=0.000),(r = 0.722) between smoking history and cervical cancer, a moderate correlation (p=0.000),(r = 0.625) between vaginal delivery history and cervical cancer, a very weak correlation (p=0.154),(r = 0.106) between contraceptive use and cervical cancer, and a weak correlation (p=0.000),(r = 0.327) between age and cervical cancer in OB-GYN patients at the Batam Free Trade Zone Hospital in 2023.

Conclusion: Based on this research, it is concluded that the null hypothesis (Hᴏ ) is rejected and the alternative hypothesis (Ha) is accepted, meaning there is a correlation between smoking history, vaginal delivery history, contraceptive use, age, and cervical cancer in OB- GYN patients at the Batam Free Trade Zone Hospital in 2023

Keywords: Cervical cancer, Smoking habits, Vaginal childbirth, Hormonal contraceptives, Age

HUBUNGAN MOBILITAS FISIK TERHADAP RISIKO JATUH PADA LANSIA DI MT HUSNUL KHOTIMAH TAHUN 2024

Yani Christina — 2025-06-05

ABSTRACT

Background: The elderly experience a decline in physical function as they age, which can affect mobility and increase the risk of falling. Falls in the elderly can have serious consequences, including injuries and a decrease in quality of life. Limited physical mobility is one of the main factors contributing to fall incidents among the elderly.

Methods: This study employed an observational analytic design with a cross-sectional approach. The study sample consisted of 50 elderly individuals selected using a total sampling technique. Data were collected through the Timed Up and Go (TUG) test to assess physical mobility and a fall risk questionnaire for the elderly. Data analysis was conducted using the chi-square test with a significance level of 0.05.

Results: The results showed that among the 50 respondents, 66.0% had impaired physical mobility, 30.0% had good physical mobility, and 4.0% had normal physical mobility. Additionally, 88.0% of the elderly had a high risk of falling, while 12.0% had a low risk of falling. A significant association was found between physical mobility and fall risk among the elderly (p-value = 0.000).

Conclusion: There is a significant relationship between physical mobility and fall risk in the elderly at MT Husnul Khotimah Masjid Raya Batam Center. Elderly individuals with limited mobility have a higher risk of falling

Keywords: Physical Mobility, Fall Risk, Elderly

KEJADIAN MUSCULOSKELETAL DISORDERS (MSDS) DITINJAU DARI POSISI KERJA PADA PENJAHIT DI PT GARMENT BATAM TAHUN 2024

Rusdani — 2025-06-05

ABSTRACT

Background: Musculoskeletal Disorders (MSDs) are common health issues that can cause discomfort in joints, muscles, bones, cartilage, ligaments, and nerves. Workers in the textile industry, especially in the convection bussiness, are at high risk of developing MSDs due to less ergonomic working positions.

Methods: This research uses quantitative methods with a cross-sectional design to assess the relationship between work position and MSD complaints among tailors at PT Garment Batam in 2024. The sampling method used is total sampling, where all 43 tailors at PT Garment Batam are included as research subjects. The chi-square and fisher test will be used for statistical analysis.

Results: Based on the results of the fisher test, a p-value of 0.005 (p < 0.05) was obtained. This indicates a significant relationship between work position and musculoskeletal disorder complaints among tailors at PT Garment Batam in 2024.

Conclusion:. This research concludes that poor working positions can increase the risk of Musculoskeletal Disorder (MSD) complaints among tailors at PT Garment Batam in 2024.

Keywords: Work Posture, complaints of musculoskeletal disorders, Tailors

PERBANDINGAN AKURASI TAKSIRAN BERAT JANIN MENGGUNAKAN RUMUS DARE DAN RISANTO DALAM MENENTUKAN PERKIRAAN BERAT BAYI LAHIR DI PRAKTIK BIDAN MANDIRI X TAHUN 2024

Dino Gagah Prihadianto — 2025-06-05

ABSTRACT

Background: Both of high birth weight (HBW) and low birth weight (LBW) infants have the potential to develop health problems during infancy. Most of these problems are related to birth weight, which is a crucial parameter in determining the survival of newborns. Inaccurate fetal weight estimation can lead to undetected problems during pregnancy, thus necessitating research to identify the most accurate fetal weight estimation formula.

Methods: This study used a comparative design with a cross-sectional approach. The population in this study was mothers who gave birth at Midwife Practice X in 2024. The sample was determined using non-probability sampling, specifically total sampling. The results were tested using a paired t-test and receiver operating characteristic (ROC).

Results: The research results indicated no significant difference between the Dare formula (p-value 0.147) and actual birth weight; however, a significant difference was found between the Risanto formula (p-value 0.000) and actual birth weight. Based on ROC testing, the Dare formula showed an accuracy of 87%, while the Risanto formula had an accuracy of 65%.

Conclusion: Fetal weight estimation using the Dare formula demonstrated a higher level of accuracy compared to the Risanto formula in predicting birth weight

Keywords: Estimated fetal weight, Birth weight, Maternity

GINGIVA CHANGES IN DIABETES MELLITUS PATIENTS: LITERATURE REVIEW

Uswatul Husnaini — 2025-06-05

Diabetes mellitus is a chronic metabolic disease that leads to oral complications generally, including changes and damage to the gingiva due to increased inflammation. The incidence of periodontal disease is two to three times higher compared to individuals without diabetes, which exacerbates gingival tissue damage and slows down healing. Hyperglycemia triggers the formation of advanced glycation end-products (AGEs), which increase the production of pro-inflammatory cytokines. This article aims to identify changes in the gingiva associated with diabetes mellitus. The method used is a literature review of articles published online through databases such as Google Scholar and PubMed. The analyzed articles are publications from 2019 to 2024, with a total of 21 articles meeting the inclusion criteria and relevant to the research objectives. The study results indicate that the interaction between hyperglycemia causes changes in the gingiva of diabetic patients, increased oxidative stress, and dysfunction in the immune system, which worsens inflammation and gingival tissue damage. Factors such as increased free radicals, impaired tissue healing due to vascular dysfunction, and decreased collagen production also contribute to the exacerbation of tissue damage, thereby increasing the risk of periodontal disease in patients with diabetes mellitus. Gingivitis and periodontitis are two common forms of periodontal disease caused by pathogenic biofilms around the teeth.

HUBUNGAN ANTARA EKSPRESI CASPASE 3 DENGAN PROGRESIVITAS KANKER SERVIKS STADIUM IIA2 DAN IIB POST KEMOTERAPI NEOADJUVAN RSUP DR SARDJITO YOGYAKARTA

Erika Kusumawardani — 2025-06-05

ABSTRAK

LATAR BELAKANG: Kanker serviks merupakan salah satu kanker pada perempuan yang memiliki angka kejadian dan kematian yang tinggi di Indonesia. Pada kanker serviks stadium IIA2 dan IIB dikenal modalitas kemoterapi neoadjuvan sebelum operasi radikal yang bertujuan untuk mengurangi massa tumor sehingga memudahkan pembedahan dan menghambat mikrometastasis. Infeksi Human Papilloma Virus (HPV) merupakan faktor penting penyebab kanker serviks. Protein caspase 3 yang berperan dalam proses apoptosis berkaitan dengan patogenesis kanker serviks. Sampai saat ini, belum ada prediktor yang dapat digunakan untuk memprediksi progresivitas kanker serviks stadium IIA2 dan IIB setelah pemberian kemoterapi neoadjuvan.

BACKGROUND: Cervical cancer is a cancer in women that has a high incidence and mortality in Indonesia. In stage IIA and IIB cervical cancer, neoadjuvant chemotherapy modality is known before radical surgery which aims to reduce tumor mass to facilitate surgery and inhibit micrometastatic. Human Papilloma Virus (HPV) infection is an important factor in causing cervical cancer. Caspase 3 protein which plays a role in the apoptosis process related to the pathogenesis of cervical cancer. Nowadays, there are no predictors that can be used to predict the progresivity of stage IIA2 and IIB cervical cancer after presenting neoadjuvant chemotherapy.

Kata kunci: kanker, serviks, caspase 3, progresivitas, kemoterapi